The Sloughi is largely unchanged from ancient times, and so retains a robust genetic health. Only a few genetic conditions have been noted in the breed, the most notable of which is Progressive Retinal Atrophy. Fortunately the Sloughi is one of the breeds in whom this condition can be DNA tested with a small blood sample, and breeders are working to eliminate it from the gene pool. Like all sighthounds, the Sloughi is very sensitive to anesthesia, and can be sensitive to vaccines, worming, and other medications. Sloughi owners should engage veterinarians who are familiar with sighthound. Otherwise the breed tends to enjoy excellent health into old age.